The Molecular Mechanism of Compatibility of Achyranthes bidentata and Radix Paeoniae Alba Mediating Antioxidant Damage

نویسندگان

چکیده

To explore the molecular mechanism of antioxidant damage Achyranthes bidentata and Radix Paeoniae Alba is main objective study. Rats were treated with Alba. The total protein, nuclear protein ribonucleic acid extracted. levels messenger detected by western blot quantitative polymerase chain reaction, respectively. apoptosis cells was cell viability clone formation experiments carried out. serum malondialdehyde content white peony group lower than that control group, while superoxide dismutase activity higher which statistically significant (p<0.05). level factor erythroid 2-related 2 in nucleus increased after treatment medicated serum. heme oxygenase 1 significantly percentage apoptosis, number clones those serum, indicating compatibility can promote survival under oxidative stress. Under joint action kinase C delta kinase, up-regulate expression enzymes.

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2022

ISSN: ['0250-474X', '1998-3743']

DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.407